منابع مشابه
Plant Viruses as Nanoparticle-Based Vaccines and Adjuvants
Vaccines are considered one of the greatest medical achievements in the battle against infectious diseases. However, the intractability of various diseases such as hepatitis C, HIV/AIDS, malaria, tuberculosis, and cancer poses persistent hurdles given that traditional vaccine-development methods have proven to be ineffective; as such, these challenges have driven the emergence of novel vaccine ...
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We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV)-based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine. These findings demonstrate the utility of VSV-based vaccines against divergent viral pathogens, even when preexisting immunity to the vaccine vector is present.
متن کاملRecombinant viruses as vaccines against viral diseases.
Vaccine approaches to infectious diseases are widely applied and appreciated. Amongst them, vectors based on recombinant viruses have shown great promise and play an important role in the development of new vaccines. Many viruses have been investigated for their ability to express proteins from foreign pathogens and induce specific immunological responses against these antigens in vivo. General...
متن کاملDominant resistance against plant viruses
To establish a successful infection plant viruses have to overcome a defense system composed of several layers. This review will overview the various strategies plants employ to combat viral infections with main emphasis on the current status of single dominant resistance (R) genes identified against plant viruses and the corresponding avirulence (Avr) genes identified so far. The most common m...
متن کاملMonoclonal Antibodies against Plant Viruses
It has been well established that monoclonal antibodies, since their initial description', play an important role on biological research . This technique has also been applied to studies on plant virus2·6> and this aspect was reviewed >. The basic characteristics of monoclonal antibodies are that (1) the antibody specifically reactive with one epitope can be obtained, (2) a hybridoma clone, onc...
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ژورنال
عنوان ژورنال: Virology Journal
سال: 2014
ISSN: 1743-422X
DOI: 10.1186/preaccept-2088894788140228